Upload and analyze your cardiomyocyte videos captured on any microscopy system. Use brightfield or phase contrast to analyze contractility, or fluorescence to analyze calcium signaling.
Pulse accomodates any cell culture type - single cell, monolayer, tissue, or spheroid - and will provide measurements for each distinct beating region.
Pulse's patented algorithms generate automated measurements of beat rate, beat irregularity, displacement, velocity, contraction/relaxation times, and more.
Use our desktop software (for Windows or macOS) to batch-upload folders of videos, including 96 or 384-well plate experiments.
Pulse is the simplest software that I have used to date and I highly recommend using Pulse for individuals who are interested in studying cellular phenotypes of cardiomyocytes. Using Pulse has allowed me and fellow lab members to identify cellular phonotypes that would have been impossible to identify otherwise. One great feature about Pulse is that no additional adjustments to parameters are necessary, which makes it very easy to use for scientists with limited computational background.
Pulse satisfies a significant need in the field of cardiac disease modeling. The high throughput, automated video analysis enables the efficient measurement of contractility in human iPSC-cardiomyocytes from a number of patients with diverse disease background, age group, gender and ethnicity. It also allows the study of therapeutic or cytotoxic compounds in relation to their effect on hiPSC-cardiomyocytes. Pulse is extremely user-friendly for either experienced researchers or starting students.
Using Pulse has allowed me to generate meaningful data related to cardiac physiology in a fraction of the time it took with previous technology. I can test a large number of different conditions with minimal hands-on time and the data will be ready and waiting for me at my convenience.
Pulse offers a simple and user-friendly cloud-based data storage and analysis option. The automated video analysis allows for a detailed understanding of the cell behavior such as functional properties of beating cardiomyocytes in health and disease states.